Our GoalThe overall goal of C1net is to create a vibrant community of UK researchers who will unravel the biological, chemical and process engineering aspects of gas fermentation and realise its potential through commercial application.
To achieve our goal we are:
- Bringing together a UK-based cadre of biologists, chemists, computational modellers/mathematicians and process engineers, to better understand and exploit gas fermentation processes for translation into industry.
- Encouraging participation by feedstock suppliers, technology developers, industry and end-users in the development of the technology.
- Holding a series of sandpits for the discussion and development of cross-disciplinary research projects, including proof of concept studies, to be funded through pump priming funds administered through the C1net Management Board.
- Fostering the development of major integrated grant proposals based on proof of concept studies.
- Organising annual meetings of the leading scientists from the UK, including overseas representatives, open to the wider UK community, providing an update on the latest research findings.
- Maintaining this website to provide regular updates and case studies on the research development.
- Supporting and encouraging participation and development of the PDRAs and students and providing knowledge transfer through workshops and other training activities.
ActivitiesC1net provides a number of events and activities to foster and enhance collaboration between industry and academia; inform policy makers; train the next generation of scientists and educate the general public.
2016, we commissioned a report form E4Tech entitled “The commercial and strategic opportunity offered by gas fermentation in the UK”.
2017, along with BioCatnet, P2P and CBMnet, C1net commissioned a report entitled “Developing Strategy for Industrial Biotechnology and Bioenergy in the UK”.
2018, “Opportunities of Methane Fermentation for the UK Bioeconomy”.
Sandpit Events and Partnering Meetings
We will organise regular events to help develop and pump-prime multi-disciplinary projects aimed at generating proof of concept outputs. These will involve a variety of sectors to maximise industrial involvement, and will focus on existing and future national and international funding opportunities.
We will hold regular workshops to provide training for PDRAs and PhD students in key enabling technologies, especially areas such as Gene Technologies, Gas Fermentation and Metabolic Modelling. Additional workshops will cater for emerging areas of importance.
We will hold annual scientific meetings. The first will coincide with planned visits by researchers from the CAS Key Laboratory of Synthetic Biology in Shanghai and the Center for Bioenergy and Industrial Biotechnology in Beijing, who will visit the UK as part of a BBSRC China Partnership “Utilising Steel Mill ‘Off-Gas’ for Chemical Commodity Production using Synthetic Biology”, with LanzaTech, BaoSteel, Sheffield and Oxford Brookes.
We have developed community links, especially to schools through institution specific open days and tailored school visits. Drawing on SBRC experience, we have maximised impact through engagement with events such as the “Big BangScience Fair”, “Science in the Park”, University Open days and “New Scientist Live”. We have also helped to educate and inform policy makers as well as fostering relationships with key stakeholders who can assist in developing and promoting C1net activities and outputs.
Together with the University of Nottingham, we have developed an outreach game “Game of Fuels”
We will support and encourage the participation by, and development of, the PDRAs and students of C1net members, through participation at sandpit events and the planned annual conferences. In addition, we will encourage young researcher-led joint funding awards between C1net partner laboratories.
Project LeadsThe management board is currently 12 strong, with Professor Nigel Minton
(University of Nottingham) as PI and Professor David Fell (Oxford Brookes) and strong
support from leading experts in the field from industry and academia.
Nigel P Minton – C1net Director
Nigel Minton has an international reputation for excellence in advanced molecular methods for the study and exploitation of microbial chassis. He is the Director of the BBSRC/EPSRC Synthetic Biology Research Centre (SBRC) which is focussed on making chemicals and fuels from C1 feedstocks. His research activity ranges from combating bacterial pathogens, through the development of novel cancer therapies to the sustainable production of chemicals and fuels from C1, C3 and C5/C6 feedstocks. He is the PI on a wide range of grants awards, funded by the BBSRC (sLoLa, IB Catalyst & iCASE), Innovate_UK, MRC, NIH and Europe (HORIZON 2020, Marie Curie ETN, ERA-IB and ERA-CoBioTech). He has served on many national committees, is regularly invited to speak at international conferences and has filed 21 patents. He has supervised >40 PhD students, published >150 articles (ca.10000 citations) and has an Scopus h-index of 48. He is the holder of a Royal Society Wolfson Research Merit Award.
David Fell C1net Co-Director
David Fell is a professor of Systems Biology in the Department of Biological &Medical Sciences at Oxford Brookes University. He has worked for more than 30 years on computer modelling of metabolism and its regulation. He contributed to the development of Metabolic Control Analysis and its application to the interpretation of experimental results. He has helped develop elementary modes analysis for finding all feasible routes through a network – now widely used for designing metabolic engineering strategies – as well as building and analysing genome-scale metabolic networks. He holds two BBSRC India Partnering Awards, was a partner on a BBSRC-ANR systems biology project, holds a current EraSysBio+ project with France and has recently been awarded a BBSRC-DBT grant with Professor Minton.
ManagementThe management board is currently 12 strong, with Professor Nigel Minton (University of Nottingham) as PI and Professor David Fell (Oxford Brookes) and strong support from leading experts in the field from industry and academia.
Phillip Wright is Professor of Systems Biology at Newcastle University and a Fellow of the Institution of Chemical Engineers. He is currently using synthetic biology and metabolic/biochemical engineering approaches to improve energy generation by focusing on measurement and integration of multilevel biological data (e.g. proteomic and mRNA data), mathematical tools and characterising – omics-scale data.
Arild Johannessen is a co-founder of BioProtein AS which has merged into Calysta Inc., where he holds a position as Vice President of fermentation. Calysta is a market leader in gas fermentation using methane as the sole carbon and energy source. Calysta has specialised in production of the nutritional single cell Protein FeedKind,
as well as developing processes for production of platform chemicals using patented tools for genetic manipulation of methanotrophs.
Dr. Wimalasena is a Senior Scientist at Calysta responsible for small to large scale Fermentation activities including newly developed market introduction facilities located at the Centre for Process Innovation (CPI), at Teesside, in northeast England.
Calysta is developing and commercialising FeedKind® protein, a sustainable, traceable alternative feed ingredient for fish, livestock and pet nutritional products.
Sean Simpson is the Chief Scientific Officer and Cofounder of LanzaTech, the market leader in the commercialization of gas fermentation technology using steel mill off-gas for the production of low-carbon fuels that do not compromise food or land resources.
Gary Smith is the VP R&D Biotechnology of INVISTA, one of the world’s largest integrated producers of chemical intermediates, polymers and fibres. The company’s advantaged technologies for nylon, spandex and polyester are used to produce clothing, carpet, air bags and countless other everyday products.
Stephen Poulston is a research scientist and Team leader at the Johnson Matthey Technology Centre, a corporate research centre for Jonhson Matthey. Johnson Matthey is a world leader in catalysts and process technology for the production and conversion of methane and syn-gas.
Michelle Gradley is the Director of Process Biotechnology at ZuvaSyntha Technology, (BST). BST is committed to the development of novel processes for the commercial production of commodity chemicals and fuels from syngas from carboxydotrophic acetogens.
Dr Krabben is Principal Scientist at Centre For Process Innovation Ltd, at Redcar, Teesside.
Reuben Carr is Bioprocess Team Leader at Ingenza, a worldwide leader in the application of IB and synthetic biology. Ingenza provides efficient scalable bioprocesses to manufacture chemicals,biologics pharmaceuticals and biofuels, from sustainable sources.
Dr Green is the founder and Chief Executive of CHAIN Biotechnology, an innovative fermentation company focused on high value speciality chemicals.
OutreachWe have developed community links, especially to schools through institution specific open days and tailored school visits. Drawing on SBRC experience, we have maximised impact through engagement with events such as the “Big BangScience Fair”, “Science in the Park”, University Open days and “New Scientist Live”.
Together with the University of Nottingham, we have developed an outreach game “Game of Fuels”
C1net members present at Nottingham’s Pint of Science 2017Published on 04/07/18 in Outreach
Pint of Science is an international science festival which takes place annually throughout the UK and other countries.
Nottingham Festival of Science and Curiosity 2018Published on 03/07/18 in Outreach
The Festival of Science and Curiosity is now in its 4th year, and is produced by an enthusiastic collaboration of Nottingham organisations.